Author's Reply to "Reader's Response to 'There Have Been Inadequate Warnings That Erectile Dysfuncti
In accession to our engrossment screening an 18-fold increased rate of reports to the FDA [US Food and Drug Administration] of nonarteritic anterior ischemic optic neuropathy (NAION) per 1000000 prescriptions with viagra (viagra) compared with atorvastatin (Lipitor), a recent case-control concentration found that for those men with either hypertension or a continuum of myocardial infarction (MI), the use of sildenafil or cialis (cialis) conferred an increased risk for NAION, 10.7-fold increased risk and statistically significant for those with a liberal arts of MI and 6.9-fold increased risk but not quite statistically significant for those with hypertension. Thus, in the face of increased cardiovascular risk, such as seen with hypertension or MI, there is an increased risk for NAION for those using these erectile dysfunction drugs.
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